One-step bioengineering of magnetic nanoparticles via a surface diazo transfer/azide-alkyne click reaction sequence.
نویسندگان
چکیده
We have developed an efficient conversion of amino iron oxides to carbohydrate and protein derived nanoparticles with highly conserved bioactivity through a combination of diazo transfer and azide-alkyne click technology.
منابع مشابه
One-pot procedure for diazo transfer and azide-alkyne cycloaddition: triazole linkages from amines.
[reaction: see text] A one-pot reaction for Cu(II)-catalyzed diazo transfer and Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (sometimes called click reaction) is reported. 1,4-Disubstituted 1,2,3-triazoles are obtained in excellent yields from a variety of readily available amines without the need for isolation of the azide intermediates. The reaction has a broad scope and is especial...
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ورودعنوان ژورنال:
- Chemical communications
دوره 5 شماره
صفحات -
تاریخ انتشار 2008